N-Acetyl Cysteine (NAC) (pronounced: N. A-see-til. Sis-teen.) may not be a supplement we're familiar with, but it's a nutrient we should know, as it offers many valuable benefits. Let's dig deeper into what NAC is and why we need it.

The Many Health Benefits of NAC

NAC is a form of the amino acid cysteine. Cysteine is considered a semi-essential amino acid that can be found in several foods such as beef, chicken, turkey, eggs, yogurt, other meats, and whole grains. Our body can create some NAC from other amino acids (methionine and serine) just like cysteine does; however, NAC is mainly obtained from taking a supplement.

NAC is most well-known for its antioxidant capability. Antioxidants protect our cells from the effects of free radicals, which are unstable atoms that can damage cells. Like cysteine, NAC bonds with amino acids glutamine and glycine to form glutathione, a powerful antioxidant. NAC also assists with replenishing the body’s glutathione stores. Glutathione is the primary component of glutathione peroxidase, one of the most powerful antioxidant enzymes in our bodies. Together, they help convert destructive molecules, including free radicals, into harmless compounds, reducing oxidative stress. 

Another benefit NAC has is promoting healthy liver function by improving liver detoxification pathways through its production of glutathione. Glutathione is our body's most potent and self-made detoxification compound, which aids with lessening potential side effects of environmental factors such as exposure to toxins and heavy metals that may impair the liver and other organs.

Though there isn’t a daily requirement of NAC, a standard amount between 500–1,500 mg daily in divided doses has been found to be effective, and higher amounts up to 2,000 mg daily have been shown to be safe. Be sure to consult with a medical practitioner before adding in NAC if you have certain health issues or are on medications.